Five year old girl wins the battle gainst a rare liver transplant

Paridhi with the doctor team and her parents, after the successful operation

About three months ago, Mamta reached the liver department of the Gurgaon-based Medanta hospital. She hardly had any hope left with her to see the face of her five-year-old daughter named Paridhi. Earlier, she and her husband had visited several doctors in Mumbai who could not give any positive sign, and said that the case was far too advanced for a liver transplant.

However, with the shared determination of the doctors and her parents, Paridhi was saved from her complex health condition. As per Mamta, she donated 20% of her liver. She said that she and her husband Nitin were well aware that this transplant would be very risky due to her daughters low-oxygen state, but they finally took the chance as a last resort and said that God have heard their prayers.

Dr A S Soin  Medanta’s Chief, Liver transplant Surgeon who led the team said: “We had a long experience of operating milder cases of hepatopulmonary syndrome where liver failure affects the lung circulation and in extreme cases it results in respiratory or lung failure but we had never taken on such an advanced case with nearly 50 % shunt fraction before.”

Explaining the patient’s state of health prior to the transplantation, Dr Neelam Mohan director of children’s liver diseases and transplantation, said: “Paridhi had been suffering  from biliary atresia since her birth, for which an operation at 2.5 months did not prove successful. Her condition deteriorated and had life threatening liver infections with eight prolonged admissions in hospitals. And when she came to us she was deeply jaundiced. She had growth failure and severe HPS with oxygen saturation less than 70 % causing breathlessness. We took her up as one of the most challenging cases and carried out an intensive nutrition and medical preparation to take her through the transplant successfully.”

According to her, Paridhi’s post-operative treatment was also a challenge as the low oxygen state takes several weeks to correct. Nitric oxide, high external oxygen, ventilator support and temporary breathing route (Tracheostomy) have been necessary for many days. In fact, she was on ventilator support for four weeks post operation.

Dr Naresh Trehan, CMD and Chief of the Heart Institute explains,“Paridhi’s case was easier to handle at Medanta as they use nitric oxide therapy and artificial lung machine quite often in patients with serious heart diseases affecting the lungs.” Medanta’s strong multidisciplinary expertise came to the rescue, he felt.

Eventually, Paridhi was discharged from hospital after the surgery followed by 33 days of observation. She is now breathing normally without extra oxygen and will grow like a normal child with a healthy life. The joint effort put by the doctors in the hospital saved the life of Paridhi. The transplant was exceptional and one-of-its kind in India.

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